Distribution of the dhfr haplotypes in Africa

 

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Haplotypes combining codons 51, 59 and 108 are displayed

There are 5 common types: the sensitive haplotype NCS, the single mutant 108 haplotype is NCN, and the double mutants 51+108 and 59+108 haplotypes are ICN and NRN respectively. The triple mutant 51+59+108 IRN is the most highly resistant haplotype of all.

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 Samples tested

 of which positive

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Map key: percentage of data set found to exhibit mutation

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Map Key

Percentage of data set found to exhibit mutation

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